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Thursday, 24 January 2008

Vioxx | First Lawsuit

The first lawsuit against Vioxx was filed by Carol Ernst for the death of her husband from a heart attack in 2001. In 2005 the Texas jury in the trial found Merck liable and made an award of $24 million to Carol Ernst for mental anguish and loss of companionship, and a further award of $229 million in punitive damages.

This was seen as the tip of the iceberg and it was at that time estimated that Merck's liabilities could run up to something like $25 billion.

By the time of this verdict, over 4,000 lawsuits against Merck had been filed. The drug had been recalled by Merck in September 2004, following growing concerns over the dangers it caused.

Ref: CNNMoney.com


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Monday, 7 January 2008

Cardiac Arrest

There is concern about the incidence of cardiac arrests suffered by patients in hospital. This is due to the fact that defibrillation procedures could often not be carried out within the first two critical minutes.

A Norwegian study:
Our findings indicate that defibrillation should have priority during the first 3 minutes of VF/VT. Later, patients benefit from CPR in conjunction with defibrillation. Patients presenting with non-shockable rhythms have a grave prognosis, and the outcome was not associated with time to BLS or CPR quality.
VF/VT=ventricular fibrillation/pulseless ventricular tachycardia
CPR=cardiopulmonary resuscitation
BLS=basic life support



Ref:
The early minutes of in-hospital cardiac arrest: Shock or CPR? A population based prospective study
Eirik Skogvoll and Trond Nordseth


Sunday, 6 January 2008

A brief history of Vioxx

Vioxx is a branded name of the nonsteroidal anti-inflammatory drug called rofecoxib. It was developed by Merck & Co. for the treatment of osteoarthritis, conditions of acute pain, and dysmenorrhoea. Rofecoxib was also marketed under the brand names Ceoxx and Ceeoxx.

It was approved by the FDA in May 1999 and was widely used by physicians worldwide.

However, there were growing concerns that its use led to higher risk of heart attack, and Merck voluntarily withdrew it from the market.

It is estimated that Vioxx or the other brands had been prescribed to over 80 million people around the world and Merck had sales of about US$2.5 billion from Vioxx prior to its withdrawal.


See Rofecoxib.

Tuesday, 1 January 2008

Vioxx Verdicts

Personal injury law suits, as in the Vioxx cases, are a big time legal practice in the US. There are even lawyers who specialise as Vioxx attorneys. In few other countries, if any, do the laws grant comparable awards by way of compensatory and punitive damages against defendant corporations, though the trend to increased amounts is on the rise.

In the US, known for its litigious mentality, the small aggrieved plaintiff can look to huge damages for injury caused by the big medical firms and corporations. Law firms who take up such cases are as a rule paid on a contingency basis. That is they get a cut from the amount of damages awarded. And usually quite a large cut. The ethics of such a system is a matter of debate. On the other side, the big corporations also pay huge fees to their attorneys to defend their case.

In one Vioxx case an elderly gentleman called Leonel Garza was awarded $7 million in compensatory damages for suffering a heard attack after taking Vioxx. That verdict caused some outcry as Mr Garza was already overweight, suffered from high cholesterol and had a history of a previous heart attack and bypass surgery. The evidence was not even that clear that Mr. Garza was prescribed or that he took Vioxx at all. One doctor said he only gave a sample pack of 8 pills, against Garza's widow's testimony that he had given him an eight days worth sample. And another doctor denied her testimony that he ever gave Garza a 30 day Vioxx prescription or even any Vioxx prescription.

Despite what appears to be weak evidence the jury found for Mr Garza. A sympathy verdict.

Click link for more on the Garza Vioxx case.

No doubt medical firms have to be held to the highest standards. But when people see that huge payouts can be achieved even in a very weak case, that feeds and encourages the litigious instinct. Further there is always a chance of a big settlement when the big firm would rather have a case brushed under the carpet than to fight it in the full glare of an open court trial.

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